Metabolic changes underlying 31P MR spectral alterations in human hepatic tumours
نویسندگان
چکیده
منابع مشابه
Ischaemic and Metabolic Treatment of Hepatic Tumours
For treatment of malignancies, physical and metabolic differences between tumour cells and host cells have guided the development of new approaches. In this review, two new approaches to be used in the treatment of liver malignancies are outlined: ischaemic therapy and interferences with the glucose metabolism. Ischaemic therapy of liver malignancies has been used in different forms during the ...
متن کاملNormalized metabolic stress for 31P-MR spectroscopy studies of human skeletal muscle: MVC vs. muscle volume.
A critical requirement of submaximal exercise tests is the comparability of workload and associated metabolic stress between subjects. In this study, 31P-magnetic resonance spectroscopy was used to estimate metabolic strain in the soleus muscle during dynamic, submaximal plantar flexion in which target torque was 10 and 15% of a maximal voluntary contraction (MVC). In 10 healthy, normally activ...
متن کاملMetabolic alterations underlying Bevacizumab therapy in glioblastoma cells
Anti-VEGF therapy with Bevacizumab is approved for glioblastoma treatment, however, it is known that tumors acquired resistance and eventually became even more aggressive and infiltrative after treatment. In the present study we aimed to unravel the potential cellular mechanisms of resistance to Bevacizumab in glioblastoma in vitro models. Using a panel of glioblastoma cell lines we found that ...
متن کاملSpectral Editing in 31P NMR Spectra of Human Brain
There are a number of NMR experiments designed to simplify complex spectra. For example, spin-echo techniques have been used in ‘H NMR of intact cells and tissues to suppress broad background resonances from proteins and allow observation of resonances from small metabolite molecules (1-3). In this case discrimination between resonances is based on differences in T2. In other experiments differ...
متن کاملInterleaved Multivoxel 31P MR Spectroscopy
PURPOSE Separate measurements are required when investigating multiple exercising muscles with singlevoxel-localized dynamic 31 P-MRS. With multivoxel spectroscopy, 31 P-MRS time-series spectra are acquired from multiple independent regions during one exercise-recovery experiment with the same time resolution as for singlevoxel measurements. METHODS Multiple independently selected volumes wer...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: NMR in Biomedicine
سال: 1998
ISSN: 0952-3480,1099-1492
DOI: 10.1002/(sici)1099-1492(1998110)11:7<354::aid-nbm515>3.3.co;2-e